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Reformation: a rational movement of the 21st century with the aim to reform  outdated doctrines of 'alternative' medicines of the 20th century.


Sept. 2009 Posted by the Grand Master

Why We Study Biochemistry

© Prof. (Dr. of Med.) Charles McWilliams 2009

In the Universe, everything sings except most human voices: plants, animals, waterfalls, the stars, the rain, our bones and glands, and many things we do not even see; even silence makes a sound most humans can’t hear. Sound therapy takes many forms as you will learn in this article, and is a uniquely potent form of energy medicine that can unlock the vibrational forces for healing. Sound is also one of the simplest, most direct routes to achieve a sense of profound calm that allows us to move into that peaceful inner place as a religious experience. Sound is also a medium that resonates our entire organism, realized or not. Sound is also behind the action of potent biochemicals called ligands. For man’s entire history, the therapeutic value of music, religious incantantations and sound were considered indivisible from their own nature. Specific sounds, chants and music were played by humans and used a form of natural medicine . Music and chanting have been always implemented to induce, transmit, and transform diverse realms of perception (sensorial, emotional, cognitive), becoming one of the most effective mediators of emotional communication at a psychic, interpersonal, and even transpersonal dimension of experience. Today, this observation is mostly lost in a sea of electronic pollution and artificial media while humans become ever more tense, dense, toxic, and sick. Part of this illness complex is a speech impediment, however subtle, is our inability to vocalize certain musical notes. Bad habits we know are the doom of a healthful lifestyle, this we know. But speech impediments and voice habits, whether cultural, acquired, or from psychological disturbance, are very much part of this ignored complex in therapeutics. The spectrogram of the range of human voices reveals its rich harmonic content. The vocal folds, in combination with the laryngeal articulators, are capable of producing highly intricate arrays of sound, both therapeutic and pathologic. The tone of voice may be modulated to suggest emotions such as anger, surprise, or happiness. Singers use the human voice as an instrument for creating music. What we have to now realize is that our own healing potential is obstructed by the very words we utter, stammer, clammer or weap.


The voice condition called Muscle Tension Dysphonia is a mild form of Spasmodic Dysphonia, also called the strangled voice . It is defined as momentary disruption of the voice caused by involuntary movements of one or more muscles of the larynx (or voice box). The term spasmodic dysphonia loosely means a bad voice caused by muscle spasms of the larynx. A bad voice is recognized by someone as an irritating, strangled voice; a voice from a person with a bad cold or post?nasal drip; words that breaks up in whispers or even voice tremors with facial tics, neck or back spasms, and other unusual behavioral manifestations accompanying speech. Everyone knows someone with muscle tension dysphonia.

Spastic Dysphonia is listening to someone painfully choke out the words, barely audible to irritating, unintelligible and unable to communicate, which create terrible first impressions, socially and professionally. As do those with strangled voices, stutterers continue to compensate, sometimes developing voice tremors, facial tics, neck or back spasms, and other unusual behavioral manifestations, calling ailing attention to themselves.

This description of the voice problem makes no assumptions about the cause but in the majority of cases it is functional rather than organic. It is largely considered due to internal muscle tensions. Muscle Tension Dysphonia is a milder and more common form, and can sound like spasmodic dysphonia when severe or provoked during stress. Scott Adams and Robert Kennedy were among the famous people with spasmodic dysphonia as well as Katherine Hepburn and Linda Thompson, the British folk rock musician. Speech, language and communication disorders affect a significant portion of the global population. By a strict classification, only 5% to 10% of the population have a completely normal voice (with respect to all scientific parameters), all others suffer from one speech disorder or another – stammering, stuttering, lisps, slurring, cluttering, etc. It is estimated that 25% of the adult population has some form of frank MTD, exhibiting a raspy, deep, chaotic voice. Stuttering is also quite common, about 7% of the population suffer from it at some point in their life.

Dysphonia, incomplete functionality of the vocal folds, is heard as an unusual roughness of the voice, or chaotic or jerky utterance. Based on how the voice sounds, doctors have described two types:

1. adductor type, where the vocal folds close too tightly, resulting in a strained, strangled voice like Humphrey Bogart in Casa Blanca, and
2. abductor type, where the vocal folds do not close completely, resulting in a breathy voice or soundless breaks in voice like Peter Lorre (in Casa Blanca).

While much is written about the different types, both problems are an imbalance of airflow (breathing), neural dystonia resulting in muscle spasms, and vocal cord vibration. There is no characteristic voice sound for mixed SD, but a careful evaluation of the voice will identify both the strained, strangled voice characteristics of adductor SD and the breathy voice or soundless voice breaks of abductor SD. Anxiety or fatigue makes symptoms more noticeable. The good news is that MTD can be cured by massage therapy designed to relieve the tension while teaching the patient how to use correct speech techniques and learning to vocalize the tones they do not use in everyday speech. MTD responds very favorably to laryngeal massage using transdermal microcurrent, while using frequencies both transdermal and audibly that the patient is unable to articulate. This therapy returns the notes of life to the patron, improves dramatically their interpersonal relations, and offsets bad habits contributing to the a toxic lifestyle.

To date, there is no medical diagnostic test for spasmodic dysphonia, other than the observation by laryngologists and speech therapists. However, with the Jade approach and relatively simple software, you can quickly analyze tonal deficits by speaking into a computer microphone. Most people will exhibit tonal deficits whether suffering from MTD or not! In fact, this quick diagnosis, leads to a bonanza of therapeutic potentials. The premise of our new therapeutics is that the voice and body generates a set of unique frequencies in the form of harmonics, notes, and tones. Every person, as they speak normally, emit some of these frequencies that correspond to the musical scale. This musical scale is comprised of C, C#, D, D#, E, F, F#, G, G#, A, A#, and B. These will be in a range of about 2 to 3 octaves according to that individual’s voice, male or female. Many speech analysts believe that ALL 12 NOTES should be included in a healthy person’s voice to which a study of medical history concurs. If there are notes missing in that individuals voice pattern, then that missing note (element), or notes, will correspond to some deficiency in the body’s harmony. This deficiency can be corrected by applying those missing notes to strategic acu-points, or troubled areas of the body. These frequencies can be delivered audibly, transdermally, and orally by water saturated with sound frequency.

Sound too simple?

This concept of mind/body/sound has profound biologic validity. Dr. Candace Pert, in her groundbreaking book Molecules of Emotion, is a neuroscientist whose extraordinary career began with her 1972 discovery of the opiate receptor responsible for the acupuncture effect. She provides startling and decisive answers to these and other challenging questions that scientists and philosophers have pondered for centuries. Molecules of Emotion is a landmark work for sound therapy, giving a striking conclusion that it is our emotions and their biological components that establish the crucial link between voice, mind and body. This understanding of the power of our voice, minds and our feelings affecting our health and wellbeing is actually the wheel of life . It also provides a profound, new understanding to psychology, homeopathy and herbal medicine. Further, it strikes the core of medical astrology as proposed by Hippocrates, Ptolemy, St. Thomas Aquinas, Kepler, Culpepper, Paracelsus, and many others. Her pioneering research on how the chemicals inside our bodies form a dynamic information network, linking mind and body is revolutionary. By demonstrating the biomolecular basis for the relation between sound and emotions, and explaining these new scientific developments in a clear and accessible way, Pert empowers us to understand ourselves, our feelings, and the connection between our minds and our body in ways we could never possibly have imagined before. From explaining how there is a scientific basis to popular wisdom about phenomena such as "gut feelings" to making comprehensible recent breakthroughs in understanding the function of enzymes and ligands, and even sound therapy, we know can work in comfort using our therapies of legend and legion.

Biochemistry 101
The nuts and bolts of how body and mind are one —the new paradigm of biochemistry— involves some simple biology. To begin with, virtually every cell membrane in the body is studded with thousands of tiny structures called receptors. Like our sense organs—the eyes, nose, tongue, skin and ears—the job of the receptors is to pick up signals coming at them from the surrounding interstitial space. This interstitial space is also called the lymphatic fluid. Receptors so important that a full 40 percent of our DNA is devoted to making sure that they’re perfectly reproduced from generation to the next. These receptor sites are now blocked to some degree by a full 80% or more of the world’s population, accounting for epidemic diabetes and hypothyroidism. But this is another vast subject for an article at another time. The most interesting aspect to this new knowledge is that the ligands can only act through the medium of water, the basis of life itself. Once the receptors receive a signal, the information is transferred by water molecules to deep within the cell’s interior, where tiny engines resonate into action and initiate key processes called the sound of life . Data coming in this way directs cell division and growth, cell migration for tissue harmony and replication, attacking enemies and making repairs, and cell metabolism to conserve or spend energy — to name just a few of the receptor-activated activities. The signal comes from other cells and is carried by a juice that we call an informational substance. These juices from the brain, sexual organs, gut, endocrine glands, and heart communicate information from cell to cell, providing an infrastructure for the ‘conversation’ going on throughout the body/mind. You know these juices as hormones, neurotransmitters, and peptides, and scientists refer to all three with one word: the ligand.

The ligand is virtually the centerpiece of biology. This term is from ligare, a Latin word meaning “to bind,” and is used because of the way that the substances latch on so tightly to the cell’s surface receptors. Information carrying ligands are responsible for 98 percent of all data transfer in brain to body. The remaining 2 percent of communication takes place at the synapse, between brain cells firing and releasing neurotransmitters across a gap to hit receptors on the other side. In the video What the Bleep . . . !?, audiences saw an animated electrical storm taking place in the brain to show what this synaptic activity looks like. But what they didn’t see is that there are neurons within this same electrical sparking activity, firing throughout the body, not just in the brain. These interlocking neurons actually form the basis of acupuncture therapy.

There are over 200 peptides that have been mapped in the brain and body to date, each one sounding a complex emotional chord —such as bliss, hunger, anger, relaxation, or satiety— when their signal is received by the cell. One of these peptides discovered by Pert was endorphins, the opiate substance released by the brain during acupuncture. When these signals are not received, as in lymphatic stasis, toxic receptor blockage (when a toxin binds with a receptor to permanently destroy or extinguish it), we have major problems with body harmony. The common denominator of this occurrence has been labeled as metabolic syndrome X, or silent inflammation.

Everyone should know that most ligands have chemical equivalents found outside the body, such as Valium, marijuana, cocaine, alcohol, and caffeine, to name a few. But what we are now discovering is that herbal medicines act as therapeutic ligands also. A constituent of St. John's wort with potent antidepressant activity, is a potent ligand (K(i)= 27 nM) for the pregnane X receptor, an orphan nuclear receptor that regulates expression of the cytochrome P450 (CYP) 3A4 monooxygenase. Cytochrome P450 enzymes are a superfamily of mono?oxygenases that are found in all kingdoms of life – enzymes that constitute a large super family of haem?thiolate proteins involved in the metabolism of a wide variety of both exogenous and endogenous compounds.

So What Have You Learned?

You’ve now learned about the two components that make up this body/mind communication system—the receptor and the ligand. These are what Pert called the ‘molecules of emotion.’ You also have learned about water, which carries the frequencies that makes the receptor ring to the tune of the ligand. So let’s now ring the school bell!

But, exactly how do the ligand and receptor find each other across the vast reaches of the intercellular space, and then transfer vital information to affect cellular activity? Biologists continue to explain the attraction by a quality called receptor specificity, which is that each receptor is specifically shaped to fit one, and only one ligand. A lock-and-key model helped with visualizing this archaic, schoolboy understanding of connectivity or binding. The ‘key’ (a peptide) floats by until it finds its perfect ‘keyhole’ (the receptor). Key inserts into the keyhole, opening the ‘lock’ of the cell, and cellular activities begin. So doctors, now you can safely prescribe your drug?

While this is only partially accurate, we now understand a more dynamic relationship between ligand and receptor, involving something called vibratory attraction, or more simply sound resonance. Sitting on the surface of the cell, the receptors wiggles and vibrate, changing from one configuration to another in a constant state of sound resonance. This dance creates a vibration that resonates with a ligand vibrating at the same frequency, and they begin to resonate together.

Resonance occurs like when you pluck one string on two different guitars in the same room, one will resonate with the other, both humming the same note. But when the guitar is out of tune, plucking creates dissonance, cell harmony begins to break down, and the body’s orchestration begins to miscommunicate, if not break down and die. The same occurs with prolonged light deprivation, however in this case it is sound deprivation.

Cellular resonance creates a similar force of attraction, the way that peptides resonate with their receptors and come together to strike that bio-emotional chord as they bind. And that’s when the music begins! Sound and the emotions are the link between the physical body and nonphysical states of consciousness, and the receptor-binding site is where this happens! The attracting vibration is the emotion, and the actual connection—peptide to receptor — is the manifestation of the sound in the physical world. That’s why Pert called peptides and their receptors the molecules of emotion.

Water is the Key

We can now safely discard the notion of the lock and key mechanism , in favor of a new understanding as water as the key. Water is the key to understanding homeopathy, rife frequencies, herbal teas, and sound therapies. Just as sharks detect prey from a long distance by detecting any chemical emissions such as blood in water as little as one part per million from a kilometer away, the cells of our bodies do similar. Once a remedy in water reaches the blood, the body resonates. We have known for decades that herbs are best delivered in the form of tea, rather than capsules. Tea, on a empty stomach, by-passes the digestive juices which, along with gut hydrochloric acid, would not doubt drastically modify if not fatally mortify, the life giving ligands. Homeopathics, we know are best retained in the mouth without swallowing, allowing it to take a similar course. Rife frequencies, originally delivered by Rife himself through air, are best delivered by contact electrodes on the skin, bypassing the electromagnetic shielding effects of the durable epidermis. And better, rife frequencies, delivered by iontobaths™, developed by the author, allows vibrationally treated water and therapeutic ions to enter the blood direct by electrosmosis. Add to that the notes of essential oils, and you truly have revolutionary therapy.

Therapy Revolution

The author is researching a radically new and simple voice analysis and sound healing technique that involves the analysis of voice sound waves produced during vocalization. It is generally found that most people have a tonal deficit of one of the musical notes, indicating they are unable to resonate that tone in their own body. This relationship between the musical notes and the organs, glands and the organism’s function, has been developed by the author over the last twenty years of clinical research.


To observe the various frequencies in your voice using the Vocal Analysis software, you first speak into a computer microphone generating a bar graph which reveals the amplitude of various notes in your voice. Research conducted by many practitioners has repeatedly demonstrated that the sound frequencies in your voice relate to the state of your physical structure, biochemical functions, emotions, mental processing, and environmental influences. Tonal deficits are the norm. We could say everyone has a music hunger just as one also has a color hunger. We subconsciously seek out these desires through music, color clothing and environment, even our mates, etc. This magnetic hunger can be so strong as to lead to addictions. It is actually the driving force of the entire psyche.

Voice Disorders, the Norm

Voice disorders result from a variety of local and systemic conditions. Some patients have poor vocal quality or strength due to lesions such as a laryngeal neoplasm or chemical injury (smoking), neuromuscular weakness, voice abuse (talking incessantly) or psychological stress. Diseases of neuromuscular weakness, abnormal muscle tension and disorders of central neurologic control are the norm, and will cause poor speech articulation and poor voice quality. This will dramatically affect all our relations with others, our family, our business, virtually every interpersonal relation, day to day, hour to hour. What can be more dramatic upon one’s wellbeing?

Many voice disorders are associated with a weakness, incoordination or abnormal use of facial and cervical muscles, e.g. tics. Normal voice production requires movement and harmonization of the larynx by the extrinsic laryngeal muscles in the neck. This is learned from early childhood and modified by psychocultural development, often to little fault of our own. The facial musculature is dramatically affected as an extension of the cervical muscles and is a primary component in the formation of language.

Tone of the facial and cervical muscles also has an influence on vocal resonance in the oral cavity and pharynx. Weakness of these muscle groups may result in complaints such as hoarseness, breathiness, loss of vocal volume, loss of pitch range, vocal fatigue, dysarthria and slurred speech. Conditions causing such weakness include cerebrovascular accident (stroke), chronic neuromuscular diseases (i.e. multiple sclerosis, ALS), myasthenia gravis, surgical trauma, Bell's palsy, Parksinson’s, and any chronic debilitating disease also obviously affects voice quality. But we all at some point succumb to some form of a voice defect through the stress and routine of life, whether early in the morning, or on the way home from work. Are we durable enough to sustain our emotional health and integrity?

Excessive or "imbalanced" activity of the intrinsic and extrinsic laryngeal muscles affects phonatory function and is considered an important etiologic factor contributing to a spectrum of interrelated symptoms and syndromes including muscle tension dysphonia (MTD) and a worse condition known as spasmodic dysphonia (SD). Recognition of the contribution of laryngeal and paralaryngeal hypertonicity is critical to proper diagnosis and selection of suitable treatments, regardless of the presumed cause of the voice disorder. This is why author’s famous facial and laryngeal massage treatments can be so helpful for these conditions, no matter the severity. Just like a chiropractic adjustment, everyone can use a Facial massage treatment.

Aronson (1980) proposed that all patients with voice disorders, in spite of etiology, should be evaluated for excess laryngeal muscle tension, either as a primary or secondary origin of the continuing speech dysphonia. As explained at this site , it was found that laryngeal massage was employed most often for patients whose voice problems were without a definitive etiology, actually the majority of people with “functional” speech disorders. Most commonly, circumlaryngeal massage is used for those diagnosed with hyperfunctional disorders such as Spasmodic Dysphonia and its milder form, Muscle Tension Dysphonia, affecting a vast majority of the population. In addition, professionals such as singers and public speakers have found the technique to be vitally helpful.

Spasmodic Dysphonia: A Peculiar Voice Disorder

Jade Academy

School of Natural Medicine

Books by the Author





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